Focused ultrasound trial for rare sarcoma halted early
NCT ID NCT04123535
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether focused ultrasound could partially destroy a rare soft-tissue cancer called undifferentiated pleomorphic sarcoma and boost the body's immune response. Only 5 people were enrolled before the trial was terminated. The main goal was to check safety and see if the treatment changed immune cell levels in the blood.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Magnetic Resonance-guided Focused Ultrasound (MRgFUS) device
What this could lead to
If successful, this approach could help the immune system fight sarcoma more effectively, potentially improving treatment options.
What could go wrong
The trial was terminated early and enrolled only 5 people, so results are very limited. The approach is still experimental and may not work for everyone.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of California, San Francisco
San Francisco, California, 94143, United States