Poop pills aim to stamp out superbugs in the gut

NCT ID NCT07106580

Recruiting now Disease control Sponsor: University of Rijeka Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether capsules containing freeze-dried stool from healthy donors can safely remove multidrug-resistant organisms (MDROs) from the intestines of 48 adults who carry these bacteria without symptoms. Participants will take either the fecal transplant capsules or a placebo over 3 days and be monitored for 6 months. The goal is to see if this approach can decolonize the gut and prevent future infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lyophilized fecal microbiota transplantation (FMT) capsules
What this could lead to: If it works, this could offer a simple, pill-based way to eliminate dangerous drug-resistant bacteria from the gut, reducing infection risk.
What could go wrong: This is an early Phase 1/2 trial with only 48 participants, so results may not apply broadly. The treatment may not clear the bacteria, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Asymptomatic Infections

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLONIZATION, ASYMPTOMATIC

Contacts and locations

Locations

Clinical Hospital Center Rijeka
RECRUITING

Rijeka, 51000, Croatia

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