New drug aims to stop breast cancer return in women with gene mutations

NCT ID NCT07353437

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether adding the drug fluzoparib to standard treatment after surgery can help prevent breast cancer from coming back in women with certain inherited gene mutations (HRR). About 334 women with early breast cancer will be randomly assigned to receive either fluzoparib plus standard care or standard care alone for one year. The study measures how long women remain free of invasive cancer.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Fluzoparib
What this could lead to
If successful, this could offer a new targeted treatment option to reduce the risk of breast cancer returning in people with specific genetic mutations.
What could go wrong
This is an early phase 2 trial, so results are not yet proven. The drug may cause side effects or not improve outcomes compared to standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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