New drug combo targets tough brain tumors in kids

NCT ID NCT02115074

Completed Disease control Sponsor: Centre Oscar Lambret Source: ClinicalTrials.gov ↗

First seen Mar 23, 2026 · Last updated May 11, 2026 · Updated 5 times

Summary

This early-phase study tested a combination of two drugs, Fluvastatin and Celebrex, in 20 children and young adults with certain types of brain tumors (gliomas) that had come back or not responded to standard treatments. The main goal was to find the safest dose of Fluvastatin when given with a fixed dose of Celebrex. The approach aims to control tumor growth with fewer side effects than standard chemotherapy.

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Contacts and locations

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Locations

CHU Angers

Angers, 49933, France
Centre Hospitalier de Nancy

Vandœuvre-lès-Nancy, 54511, France
Centre Hospitalier de Purpan - Hôpital des Enfants

Toulouse, 31026, France
Centre Hospitalier de Strasbourg

Strasbourg, 67098, France
Centre Léon Bérard

Lyon, 69373, France
Centre Oscar Lambret

Lille, 59020, France
Hôpital pour enfants La Timone

Marseille, 13385, France
Institut Curie

Paris, 75005, France

Conditions

Explore the condition pages connected to this study.

GLIOMA