Toothpaste showdown: prescription vs. Over-the-Counter fluoride levels measured
NCT ID NCT05601154
First seen Mar 17, 2026 · Last updated May 19, 2026 · Updated 9 times
Summary
This study looked at how much fluoride stays in saliva after using different toothpastes and mouthrinses. Twenty healthy adults tried four combinations of toothpaste (regular or prescription-strength) and mouthrinse (with or without fluoride). Researchers measured fluoride levels in saliva over 60 minutes to see which combination keeps fluoride in the mouth longest. The goal is to understand how to better prevent cavities.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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School of Dentistry, University of Michigan
Ann Arbor, Michigan, 48109, United States
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