Light probe could help surgeons spot brain tumors Mid-Operation

NCT ID NCT02473380

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tested a special light probe that helps surgeons see brain tumor tissue during an operation. Eleven adults with suspected brain tumors took part. The probe uses a drug that makes tumor cells glow, and the goal was to see if the device could accurately tell tumor from healthy brain tissue in real time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

5-aminolevulinic acid (Gliolan) as a contrast agent

What this could lead to

If successful, this could lead to a real-time tool that helps surgeons remove brain tumors more precisely during surgery.

What could go wrong

This is a very early feasibility study with only 11 people. The technique may not work as well in living patients as it did in the lab, and it is not yet ready for widespread use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

glioma low grade glioma malignant glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospices Civils de Lyon

    Lyon, 69002, France