Glowing dye could help burn surgeons cut away only the dead tissue

NCT ID NCT05593523

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a fluorescent dye called indocyanine green (ICG) can help surgeons see exactly which parts of a burn wound are dead or inflamed. Up to 100 burn patients will receive the dye and have their wounds imaged with a special camera before and during surgery. The goal is to see if this technique helps surgeons remove only the damaged tissue, which could lead to better healing and fewer surgeries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Indocyanine green (ICG) dye
What this could lead to
If successful, this could lead to a more precise surgical tool to help burn surgeons remove only the dead tissue, potentially improving wound healing and reducing the need for repeat surgeries.
What could go wrong
This is an early-stage study with only 100 participants, focused on measuring imaging accuracy, not on proving better outcomes. The dye and device are already FDA-approved for other uses, but their benefit for burn surgery is not yet established.

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Conditions

The condition(s) this trial relates to.

burn Necrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Wisconsin

    Madison, Wisconsin, 53792, United States

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