Glow-in-the-Dark dye could help surgeons spot hidden cancer cells
NCT ID NCT06873815
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving a fluorescent dye called fluorescein sodium before vulvectomy helps surgeons see and remove all extramammary Paget's disease cells. About 27 adults with noninvasive or microinvasive disease will receive the dye intravenously in the operating room. The main goal is to see if this reduces the chance of leaving cancer cells behind, which could lower the need for repeat surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fluorescein sodium (a dye given by IV before surgery)
- What this could lead to
- If it works, this could help surgeons remove all disease cells during vulvectomy, reducing the chance that cancer is left behind.
- What could go wrong
- This is a small, early-phase trial with only 27 people, so results may not apply to everyone. The dye could cause allergic reactions or other complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
RECRUITINGBasking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (Limited Protocol Activities)
RECRUITINGMontvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITINGNew York, New York, 10065, United States
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Memorial Sloan Kettering Cancer Center @ Suffolk - Commack (Limited Protocol Activities)
RECRUITINGCommack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
RECRUITINGMiddletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (Limited Protocol Activities)
RECRUITINGUniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester (Limited Protocol Activities)
RECRUITINGHarrison, New York, 10604, United States
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