Could a common antifungal keep Crohn's away after surgery?
NCT ID NCT02997059
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether the antifungal drug fluconazole could lower levels of certain antibodies (ASCA) and prevent Crohn's disease from returning after bowel surgery. Thirty-five adults with Crohn's disease who had recent ileal or ileocecal resection were randomly assigned to receive fluconazole or a placebo for six months. The goal was to see if targeting a yeast in the gut could reduce inflammation and recurrence.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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CHRU, Hôpital Claude Huriez
Lille, France