Antifungal drug may tame Crohn's after surgery

NCT ID NCT02997059

First seen Apr 23, 2026 · Last updated May 15, 2026 · Updated 8 times

Summary

This study tested whether the antifungal drug fluconazole could lower certain antibodies (ASCA) and prevent Crohn's disease from coming back after bowel surgery. 35 adults with Crohn's disease who had recent ileal or ileocecal resection were randomly assigned to receive fluconazole or a placebo for 6 months. The goal was to see if targeting a common yeast in the gut could reduce inflammation and recurrence.

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Contacts and locations

Locations

  • CHRU, Hôpital Claude Huriez

    Lille, France

Conditions

Explore the condition pages connected to this study.