New flu vaccine with booster additive enters human trials

NCT ID NCT06824519

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new seasonal flu vaccine that includes an adjuvant (ZFA02) to potentially boost the immune response. The trial involves 620 adults aged 18 and older, split into low-dose and high-dose groups, with some receiving a placebo. Researchers will monitor side effects and measure antibody levels to see how well the vaccine works against four flu strains.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Influenza vaccine (split virion, inactivated, quadrivalent) with ZFA02 adjuvant

What this could lead to

If successful, this could lead to a more effective seasonal flu vaccine that provides broader protection against multiple flu strains.

What could go wrong

This is an early-phase trial (phase 1/2) with only 620 participants, so the vaccine may not prove safe or effective in larger populations. Side effects like injection-site reactions or fever are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for INFLUENZA, HUMAN are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hebei Province Centers for Disease Control and Prevention

    RECRUITING

    Shijiazhuang, Hebei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••