Scientists test supercharged flu shots on healthy volunteers

NCT ID NCT03945825

Summary

This study tested whether adding special immune-boosting ingredients, called adjuvants, to two already-approved seasonal flu vaccines would improve their safety and effectiveness. It involved 241 healthy adults aged 18-45. Researchers compared the standard vaccines to versions mixed with one of two different adjuvants, checking for side effects and measuring the body's immune response.

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Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030-3411, United States

  • Cincinnati Children's Hospital Medical Center Vaccine Research Center

    Cincinnati, Ohio, 45229-3039, United States

  • Duke Vaccine and Trials Unit

    Durham, North Carolina, 27704, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30322-1014, United States

  • Saint Louis University Center for Vaccine Development

    St Louis, Missouri, 63104-1015, United States

  • University of Iowa - Vaccine Research and Education Unit

    Iowa City, Iowa, 52242-2600, United States

  • University of Maryland Baltimore - School of Medicine - Medicine

    Baltimore, Maryland, 21201-1509, United States

  • Vanderbilt University - Pediatric - Vanderbilt Vaccine Research Center

    Nashville, Tennessee, 37232-2573, United States

Conditions

Explore the condition pages connected to this study.