One-Stop shot? study combines flu and COVID boosters for seniors
NCT ID NCT04969276
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This study looked at whether it's safe and effective to give a high-dose flu vaccine and a Moderna COVID-19 booster at the same time to adults 65 and older. 306 volunteers who had already received two Moderna shots took part. Researchers measured side effects and antibody levels to see if getting both vaccines together worked as well as getting them separately.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fluzone High-Dose Quadrivalent influenza vaccine and Moderna COVID-19 vaccine (mRNA-1273)
What this could lead to
If successful, this could show that getting a flu shot and a COVID-19 booster at the same time is safe and effective for older adults, simplifying vaccination schedules.
What could go wrong
This is a phase 2 study with only 306 participants, so results may not apply to everyone. The study is completed, but it primarily measured immune response and short-term side effects, not long-term protection.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEALTHY VOLUNTEERS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Investigational Site Number :8400001
Peoria, Illinois, 61614, United States
-
Investigational Site Number :8400002
Austin, Texas, 78705, United States
-
Investigational Site Number :8400003
Glendale, Arizona, 85306, United States
-
Investigational Site Number :8400004
Vista, California, 92083, United States
-
Investigational Site Number :8400005
Centennial, Colorado, 80112, United States
-
Investigational Site Number :8400006
San Diego, California, 92108, United States