New pill for rare bone marrow cancer shows promise in shrinking spleens

NCT ID NCT07317700

First seen Jan 09, 2026 · Last updated May 15, 2026 · Updated 28 times

Summary

This study tests a new drug called flonoltinib maleate for people with intermediate- or high-risk myelofibrosis, a rare bone marrow disorder. The main goal is to see if the drug can shrink an enlarged spleen by at least 35% and reduce symptoms like pain and fatigue. About 105 adults aged 18-80 will take either the new drug or an existing treatment to compare results.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences (IHCAMS)

    RECRUITING

    Tianjin, Tianjin Municipality, 300052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital Sichuan University

    RECRUITING

    Chengdu, Sichuan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.