New pill could ease juvenile arthritis in kids

NCT ID NCT07554495

Recruiting now Disease control Sponsor: Alfasigma S.p.A. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a daily pill called filgotinib in children aged 8 to 17 with a type of arthritis that affects multiple joints. The goal is to see if the drug is safe and helps control the disease over 18 weeks. About 65 participants will take the drug and be monitored for side effects and symptom improvement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Filgotinib (a drug taken by mouth as a tablet)
What this could lead to: If successful, this could provide a new treatment option for children with juvenile arthritis, helping control joint inflammation and improve daily function.
What could go wrong: This is an early-phase, open-label study with no placebo group, so results may not prove effectiveness. Side effects are possible, and the drug may not work for all children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

juvenile idiopathic arthritis polyarticular juvenile idiopathic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POLYARTICULAR COURSE JUVENILE IDIOPATHIC ARTHRITIS

Contacts and locations

Locations

Bristol Royal Hospital for Children
RECRUITING

Bristol, BS2 8BJ, United Kingdom
Centrum Medyczne Hipokrates S C Elzbieta I Grzegorz Grzesk
RECRUITING

Bydgoszcz, 85-092, Poland
Charité - Campus Virchow-Klinikum
RECRUITING

Berlin, 13353, Germany
ETG JustMed
RECRUITING

Warsaw, 01-696, Poland
Hamburger Zentrum fuer Kinder und Jugendrheumatologie
RECRUITING

Hamburg, 22089, Germany
Hospital Sant Joan de Deu
RECRUITING

Barcelona, 08950, Spain
Hôpital Bicêtre
RECRUITING

Le Kremlin-Bicêtre, 94270, France
Istituto Giannina Gaslini-Ospedale Pediatrico IRCCS
RECRUITING

Genova, 16147, Italy
Leicester Royal Infirmary
RECRUITING

Leicester, LE1 5WW, United Kingdom
MICS Centrum Medyczne Torun
RECRUITING

Torun, 87-100, Poland
Nottingham University Hospitals Queen's Medical Centre
RECRUITING

Nottingham, NG7 2UH, United Kingdom
Pecsi Tudomanyegyetem Klinikai Kozpont
RECRUITING

Pécs, 7623, Hungary
UZ Leuven
RECRUITING

Leuven, 3000, Belgium
Vseobecna fakultni nemocnice v Praze
RECRUITING

Prague, 12800, Czechia

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