Rare lymphoma study aims to unlock secrets of treatment success
NCT ID NCT07467317
First seen Jun 27, 2026 · Last updated Sep 09, 2026 · Updated 1 time
Summary
This study will gather information from 100 people with a rare type of lymphoma called systemic anaplastic large cell lymphoma (sALCL) who have been treated with a drug combination called BV-CHP. Researchers want to see how well the treatment works in real life and understand why it works better for some people by studying their medical images and tumor samples. The goal is to find patterns that could help predict who will respond best to this therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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May 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patient affected by systemic Anaplastic Large Cell Lymphoma treated as front line therapy with BV-CHP in clinical practice
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years; * Histological diagnosis of sALCL (ALK positive and ALK negative); * Have received BV-CHP as front-line therapy in real life setting; * Availability of histological material of initial ALCLs diagnosis: a FFPE block from an excisional/incisional biopsy must be provided for patient enrollment. FNAB and GNAB will not be considered for the study; * Signed written informed consent Exclusion Criteria: * Histological diagnosis other than sALCL; * Front line treatment other than BV-CHP; * Patients treated with BV-CHP in the contest of a clinical trial; * Refuse to sign a written informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
19 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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A.O. Ordine Mauriziano - S.C.D.U. Ematologia
Torino, Italy
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A.O.R.N. S. Giuseppe Moscati - S.C. Ematologia e Trapianto emopoietico
Avellino, Italy
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A.O.U. Città della Salute e della Scienza di Torino - S.C. Ematologia
Torino, Italy
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A.S.L. di Pescara P.O. Santo Spirito - U.O.C. Ematologia
Pescara, Italy
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A.S.S.T Papa Giovanni XXIII - S.C. Ematologia
Bergamo, Italy
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A.S.S.T. Grande Ospedale Metropolitano Niguarda - S.C. Ematologia
Milan, Italy
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A.S.S.T. Ovest Milanese Ospedale di Legnano - U.O.C. di Ematologia
Legnano, Italy
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A.S.S.T. Sette Laghi - S.C. Ematologia
Varese, Italy
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A.U.S.L. di Piacenza Osp. Guglielmo da Saliceto - U.O.C. Ematologia e Centro Trapianti
Piacenza, Italy
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I.R.C.C.S. A.O.U. di Bologna Policlinico S. Orsola - U.O. Ematologia
Bologna, Italy
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I.R.C.C.S. Centro di Riferimento Oncologico - S.O.C. Oncologia medica e dei tumori immuno-correlati
Aviano, Italy
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I.R.C.C.S. Fondazione Policlinico Universitario Gemelli - U.O.S.D. Malattie linfoproliferative extramidollari
Roma, Italy
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I.R.C.C.S. Istituto Europeo di Oncologia - U.O. Oncoematologia
Milan, Italy
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I.R.C.C.S. Istituto Tumori Giovanni Paolo II - U.O.C. Ematologia
Bari, Italy
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I.R.C.C.S. Istituto di Candiolo - FPO
Candiolo, Italy
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I.R.C.C.S. Ospedale San Raffaele - U.O. Ematologia e Trapianto di Midollo Osseo
Milan, Italy
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IRCCS Humanitas Research Hospital - U.O. Ematologia
Rozzano, Italy
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U.L.S.S. 2 Marca Trevigiana Osp. Ca' Foncello - U.O.C. Ematologia
Treviso, Italy
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U.L.S.S. 8 Berica - U.O.C. Ematologia
Vicenza, Italy
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