Could a chicory root fiber supercharge immunotherapy against skin cancer?
NCT ID NCT07686835
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This trial investigates whether adding dried chicory root fiber to standard immunotherapy helps people with advanced melanoma. The fiber is meant to increase beneficial gut bacteria, which may in turn improve immune cell activity and the body's response to treatment. About 70 participants will receive either the fiber supplement or a placebo alongside their immunotherapy, and researchers will track changes in gut bacteria and tumor shrinkage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dried chicory roots (dietary fiber)
- What this could lead to
- If it works, this could show that a simple dietary change helps the body's immune system fight melanoma more effectively.
- What could go wrong
- This is a small, early-phase trial testing a biomarker, not a direct cure. The fiber may not improve treatment response, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Medical Oncology
Nijmegen, Gelderland, 6525GA, Netherlands
Contact
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
Contact
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Universitair Medisch Centrum Groningen
Groningen, Provincie Groningen, 9713GZ, Netherlands
Contact
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
Contact
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