Computer alert aims to catch hidden high cholesterol condition
NCT ID NCT06743659
First seen Jun 26, 2026 ยท Last updated Jun 26, 2026
Summary
This study tests whether a computer alert in the electronic health record can help doctors identify patients with familial hypercholesterolemia, a genetic condition that causes very high cholesterol. About 450 adults at Brigham and Women's Hospital will be included. The alert calculates a risk score using lab results and medical history, and the researchers will check if it leads to more diagnoses and lower cholesterol levels.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Alert-based computerized decision support (a program within the electronic health record)
- What this could lead to
- If successful, this could help doctors spot more patients with familial hypercholesterolemia, leading to earlier treatment and better cholesterol control.
- What could go wrong
- This is a relatively small, early-stage study testing a computer tool, not a treatment. The alert may not change doctor behavior or improve patient outcomes in the real world.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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