Computer alert aims to catch hidden high cholesterol condition

NCT ID NCT06743659

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a computer alert in the electronic health record can help doctors identify patients with familial hypercholesterolemia, a genetic condition that causes very high cholesterol. About 450 adults at Brigham and Women's Hospital will be included. The alert calculates a risk score using lab results and medical history, and the researchers will check if it leads to more diagnoses and lower cholesterol levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Alert-based computerized decision support (a program within the electronic health record)

What this could lead to

If successful, this could help doctors spot more patients with familial hypercholesterolemia, leading to earlier treatment and better cholesterol control.

What could go wrong

This is a relatively small, early-stage study testing a computer tool, not a treatment. The alert may not change doctor behavior or improve patient outcomes in the real world.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

familial hypercholesterolemia Hypercholesterolemia Hyperlipoproteinemia Type II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact