New trial aims to settle debate: stent or meds for clogged kidney arteries?

NCT ID NCT07511309

Not yet recruiting Disease control Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at people with narrowed kidney arteries and high blood pressure. It uses a special pressure measurement (FFR) to decide who gets a stent and who gets only medication. The goal is to see which approach better protects kidney function and controls blood pressure over 12 months. About 300 participants will be enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: stent implantation and optimal medical therapy
What this could lead to: If successful, this could show that using FFR to guide stenting decisions improves blood pressure and kidney function better than medication alone.
What could go wrong: This trial hasn't started yet, and previous studies found stenting no better than medication. FFR guidance may not change that outcome.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

renal artery atheroma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATHEROSCLEROTIC RENAL ARTERY STENOSIS FRACTIONAL FLOW RESERVE OPTIMAL MEDICAL THERAPY STENT IMPLANTATION

Contacts and locations

Locations

Affilated Zhongshan Hospital of Dalian University

Dalian, Liaoning, 116001, China
China-Japan Union Hospital of Jilin University

Changchun, Lilin, 130033, China
Department of Cardiovascular Medicine, Cardiovascular Research Center , The First Affiliated Hospital of Chongqing Medical University

Chongqing, 400016, China
Frist Aiffiliated Hospital of Dalian Medical University

Dalian, Liaoning, China
Fuwai Central China Cardiovascular Hospital

Zhengzhou, Henan, 450000, China
Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College

Beijing, 100037, China
Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences)

Guangzhou, Guangdong, China
Jiangxi Provincial People's Hospital (The First Affiliated Hospital of Nanchang Medical College)

Nanchang, Jiangxi, 330038, China
Nanjing Pukou People's Hospital(Liangjiang Hospital Southeast University)

Nanjing, Jiangsu, 211800, China
Qilu Hospital of Shandong University

Jinan, Shandong, China
Qingdao Hospital University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital)

Qingdao, Shandong, China
Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine

Shanghai, 200025, China
The Affiliated Hospital of Southwest Jiaotong University, The Third People's Hospital of Chengdu, Chengdu, China

Chengdu, Sichuan, 610031, China
The First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, 510080, China
The First Affiliated Hospital of Sun Yat-sen University

Guangzhou, Guangdong, 510000, China
The Second Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, 150086, China
The Second Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, 150086, China
TianJin First Central Hospital

Tianjin, 300192, China
Zhengzhou Central Hospital Affiliated to Zhengzhou University

Zhengzhou, Henan, 450000, China
Zhengzhou Central Hospital Affiliated to Zhengzhou University

Zhengzhou, Henan, 450007, China

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