Fetal stem cells aim to tame immune chaos

NCT ID NCT03123458

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 32 times

Summary

This early-stage trial tests clonal fetal mesenchymal stem cells (cfMSCs) in 100 people with severe immune-related disorders or tissue damage. The goal is to see if the cells are safe and can reduce symptoms. Participants have no other treatment options left.

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Contacts and locations

Locations

  • Shenzhen Geno-immune Medical Institute

    Shenzhen, Guangdong, 518000, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

clonal fetal mesenchymal stem cells (cfMSCs)

What this could lead to

If it works, this could offer a new way to control severe immune disorders and reduce symptoms for patients who have no other options.

What could go wrong

This is a very early Phase 1 trial, so safety and effectiveness are not yet proven. There may be side effects, and the approach may not work for everyone.

Conditions

The condition(s) this trial relates to.

autoimmune disease graft versus host disease immune system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.