New MRI dye could spot hidden prostate cancer spread

NCT ID NCT04261777

First seen Apr 30, 2026 · Last updated May 16, 2026 · Updated 2 times

Summary

This study tested whether a special MRI contrast agent called Ferumoxtran-10 (Ferrotran®) can better find prostate cancer that has spread to lymph nodes compared to standard MRI. About 172 men with newly-diagnosed prostate cancer at medium to high risk of spread received an enhanced MRI before surgery to remove the prostate. The results were checked against tissue removed during surgery to see how accurate the scan was.

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Contacts and locations

Locations

  • Canisius-Wilhelmina Ziekenhuis Nijmegen

    Nijmegen, 6532, Netherlands

  • Charité - Universitätsklinikum Berlin

    Berlin, State of Berlin, 10117, Germany

  • Inselspital-Universitätsspital Bern

    Bern, 3010, Switzerland

  • Nederlands Kanker Instituut Antoni van Leeuwenhoek

    Amsterdam, 1006, Netherlands

  • Radboud University Medical Center

    Nijmegen, 6525, Netherlands

  • Universitair Ziekenhuis Ghent

    Ghent, 9000, Belgium

  • Universitätsklinikum Bonn

    Bonn, 53127, Germany

  • Universitätsklinikum Carl Gustav Carus

    Dresden, 01307, Germany

  • Universitätsklinikum Düsseldorf

    Düsseldorf, 40225, Germany

  • Universitätsklinikum Essen

    Essen, 45147, Germany

  • Universitätsklinikum Köln

    Cologne, 50937, Germany

  • Universitätsklinikum Leipzig

    Leipzig, 04103, Germany

  • Universitätsklinikum Schleswig-Holstein Lübeck

    Lübeck, 23538, Germany

  • Universitätsmedizin Mannheim Medizinische Fakultät Mannheim der Universität Heidelberg

    Mannheim, 68167, Germany

  • Vivantes Klinikum Am Urban

    Berlin, 10967, Germany

Conditions

Explore the condition pages connected to this study.