New surgery aims to shield fertility in women undergoing pelvic radiation

NCT ID NCT07419490

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase I trial tests a surgical procedure called utero-ovarian transposition (UOT) to temporarily move the uterus, ovaries, and fallopian tubes out of the radiation field in women aged 18-40 with pelvic cancers. The goal is to preserve fertility and ovarian function during whole pelvic radiotherapy. The study will assess safety, feasibility, and long-term outcomes like menstrual function and pregnancy potential.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Utero-ovarian transposition (surgical procedure)

What this could lead to

If successful, this procedure could allow women with pelvic cancers to preserve their ability to have children after radiation therapy.

What could go wrong

This is a small, early-phase trial with only 26 participants, so results may not apply to everyone. Surgery carries risks like complications or failure to preserve fertility.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ANAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

anal carcinoma colonic neoplasm colorectal cancer female reproductive organ cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tampa General Hospital

    RECRUITING

    Tampa, Florida, 33606, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact