New surgery aims to shield fertility in women undergoing pelvic radiation

NCT ID NCT07419490

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase I trial tests a surgical procedure called utero-ovarian transposition (UOT) to temporarily move the uterus, ovaries, and fallopian tubes out of the radiation field in women aged 18-40 with pelvic cancers. The goal is to preserve fertility and ovarian function during whole pelvic radiotherapy. The study will assess safety, feasibility, and long-term outcomes like menstrual function and pregnancy potential.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Utero-ovarian transposition (surgical procedure)
What this could lead to
If successful, this procedure could allow women with pelvic cancers to preserve their ability to have children after radiation therapy.
What could go wrong
This is a small, early-phase trial with only 26 participants, so results may not apply to everyone. Surgery carries risks like complications or failure to preserve fertility.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tampa General Hospital

    RECRUITING

    Tampa, Florida, 33606, United States

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Other studies related to the condition(s) this trial covers.