Which opioid works best for ICU patients on ventilators?

NCT ID NCT07224620

First seen Nov 06, 2025 · Last updated Jun 12, 2026 · Updated 32 times

Summary

This study looks at two common pain medicines, fentanyl and hydromorphone, for patients in the intensive care unit (ICU) who need a breathing machine. The goal is to see if one works better for managing pain and sedation. About 300 adults will take part, and researchers will track how much medicine they need and their recovery.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.