New study aims to improve care for cancer patients with fragile thigh bones

NCT ID NCT01428895

Ongoing Knowledge-focused Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 180 cancer patients whose cancer has spread to the thigh bone (femur) and who are at high risk of breaking that bone. Researchers compare outcomes between those treated with surgery alone, surgery plus radiation, or radiation alone. The goal is to see which approach best helps patients walk, manage pain, and maintain quality of life over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better predict which patients benefit most from surgery or radiation for femur bone metastases.
What could go wrong: This is an observational study, not a treatment trial. It will not test new therapies, and results may not apply to all cancer types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer femoral cancer metastatic carcinoma in the bone neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER METASTATIC MALIGNANT NEOPLASM TO FEMUR RISK OF FRACTURE

Contacts and locations

Locations

Mount Sinai Hospital

Toronto, Ontario, M5G 1X5, Canada
University Health Network, Princess Margaret Hospital

Toronto, Ontario, M5G 2M9, Canada

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