Poop pills? fecal transplant trial aims to calm IBS symptoms

NCT ID NCT05776914

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 21 times

Summary

This study tests whether a fecal microbiota transplant (FMT) from a carefully selected donor can reduce symptoms in people with moderate-to-severe irritable bowel syndrome (IBS) with diarrhea. The donor stool has low levels of certain protein-digesting enzymes and contains a specific bacteria. About 43 participants will receive the transplant via colonoscopy and be followed for 12 weeks to see if their IBS symptom scores drop by at least 50 points.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Minnesota

    RECRUITING

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.