Could a gout drug and a supplement help Parkinson's? early trial begins

NCT ID NCT07170475

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial will test the safety of combining two drugs—febuxostat (used for gout) and inosine (a natural substance)—in 24 adults with early-stage Parkinson's disease. Participants will take one of four dose combinations twice daily for 12 weeks, with regular blood tests and checkups. The goal is to see if the combination is safe and to measure changes in a blood marker called hypoxanthine, which may help guide future Parkinson's treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

febuxostat and inosine

What this could lead to

If successful, this safety data could point toward a new treatment approach for Parkinson's disease.

What could go wrong

This is a very early phase 1 trial with only 24 participants, so it may not lead to a proven treatment. Side effects like gastrointestinal upset or elevated uric acid are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fujita Health University

    RECRUITING

    Toyoake, Aichi-ken, 470-1192, Japan

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••