New nasal spray could take the edge off public speaking anxiety

NCT ID NCT06809179

Recruiting now Symptom relief Sponsor: VistaGen Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a nasal spray called fasedienol can quickly reduce anxiety in people with social anxiety disorder when they have to speak in public. Sixty adults will receive either the spray, a combination, or a placebo before a speech challenge. The goal is to see if it helps them feel less distressed in the moment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fasedienol nasal spray
What this could lead to: If it works, this could offer a fast-acting, on-demand nasal spray to ease anxiety before stressful events like public speaking.
What could go wrong: This is an early phase 2 trial with only 60 people, so results may not apply widely. The effect may be small or no better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

phobic disorder psychiatric disorder Psychological Well-Being social phobia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOCIAL ANXIETY DISORDER

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Vistagen Clinical Site
RECRUITING

Sherman Oaks, California, 91403, United States
Vistagen Clinical Site
RECRUITING

Walnut Creek, California, 94596, United States
Vistagen Clinical Site
RECRUITING

Largo, Florida, 33777, United States
Vistagen Clinical Site
RECRUITING

Saint Charles, Missouri, 63304, United States
Vistagen Clinical Site
RECRUITING

Toms River, New Jersey, 08755, United States
Vistagen Clinical Site
RECRUITING

Cary, North Carolina, 27511, United States
Vistagen Clinical Site
TERMINATED

Cleveland, Ohio, 44130, United States
Vistagen Clinical Site
RECRUITING

Plymouth Meeting, Pennsylvania, 19462, United States
Vistagen Clinical Site
TERMINATED

Plano, Texas, 75093, United States

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