Mom's voice might wake coma patients better than nature sounds

NCT ID NCT06470802

Completed Symptom relief Sponsor: Vo Thi Hong Nhan Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether playing recordings of familiar voices or nature sounds could improve consciousness, reduce pain, and stabilize vital signs in 90 critically ill coma patients in the ICU. Patients listened to 15-minute sessions twice daily for 7 days. The goal was to see which type of sound works best for awakening and comfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: auditory stimulation (familiar voices or nature sounds)
What this could lead to: If it works, this could offer a simple, low-cost way to help coma patients wake up more quickly and feel less pain in the ICU.
What could go wrong: This is a small, completed trial with only 90 participants, so results may not apply to all coma patients. The effect might be small or not last long.

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Conditions

The condition(s) this trial relates to.

Coma Critical Illness ocular motor apraxia, Cogan type Unconsciousness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMA CRITICAL ILLNESS UNCONSCIOUSNESS

Contacts and locations

Locations

Intensive Care Unit, University Medical Center Ho Chi Minh City

Ho Chi Minh City, 700000, Vietnam
Neurosurgical Intensive Care Unit, University Medical Center Ho Chi Minh City

Ho Chi Minh City, 700000, Vietnam

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