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Can brain scans and sensory tests unlock the secrets of facial pain?

NCT ID NCT05147454

Knowledge-focused Sponsor: Walton Centre NHS Foundation Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This study examines people with trigeminal neuralgia and persistent idiopathic facial pain, two conditions that cause chronic facial pain. Researchers will use sensory tests and MRI scans to look for signs of nerve damage and see how they relate to each other. The goal is to better understand what causes these painful conditions and how they affect the nervous system.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Quantitative sensory testing and MRI scans
What this could lead to
If successful, this could improve understanding of facial pain conditions and guide more targeted treatments.
What could go wrong
This is an observational study with a small number of participants, so findings may not apply to everyone and may not lead directly to new treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Nov 2021

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Consecutive patients attending The Walton Centre Clinics

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Definite diagnosis of Classical or Idiopathic Trigeminal Neuralgia or Persistent Idiopathic Facial Pain according to the latest ICOP 2020 Criteria * Naive to any surgical procedures Exclusion Criteria: * Any major chronic painful or other neurological disease * Diagnosis of Secondary Trigeminal Neuralgia * Diagnosis of other facial pain syndromes * Cognitive disturbances

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Conditions

The condition(s) this trial relates to.

Facial Pain persistent idiopathic facial pain trigeminal neuralgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Facial pain

Contacts and locations

Locations

  • The Walton Centre NHS Foundation Trust

    Liverpool, L97AL, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.