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A glimpse in the eyes: could a simple test forecast Post-Surgery confusion?

NCT ID NCT07806487

Diagnosis Sponsor: University of Chile Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This study tests whether tracking eye movements can help predict delirium, a state of confusion that sometimes occurs after surgery in older adults. Researchers will measure eye movements in 40 patients aged 70 and older before they undergo moderate- to high-risk surgery. They will then check if these measurements correlate with the development of postoperative delirium, aiming to provide a noninvasive early warning tool.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Eye movement tracking as a diagnostic biomarker
What this could lead to
If eye tracking predicts delirium, doctors could identify at-risk patients early and intervene sooner, potentially reducing complications.
What could go wrong
This is a small pilot study, so results may not apply broadly. Eye movements might not reliably predict delirium in all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Older adult patients scheduled for moderate- to high-risk surgeries at the Hospital Clínico de la Universidad de Chile. The cohort is drawn from the elective surgical scheduling pool of the institution, aiming for a balanced distribution across biological sex and age ranges within the target demographic.

Ages

70 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 70 years or older. * Scheduled for moderate- to high-risk elective surgery, defined as a procedure requiring a postoperative hospital stay of at least 3 days. * Able to provide signed, written informed consent. Exclusion Criteria: * Presence of delirium at baseline admission, evaluated via the Confusion Assessment Method (CAM). * Use of neuroleptic/antipsychotic medications within the past 6 months. * Prior history of dementia (including Alzheimer's disease, vascular dementia, or mild cognitive impairment). * History of encephalopathy. * Psychiatric disorders presenting with psychosis. * Brain injury with neurological sequelae (e.g., prior stroke, traumatic brain injury). * Visual acuity is insufficient to complete the automated eye-tracking tasks. * Illiteracy. * Non-Spanish speakers. * Concurrent participation in any other clinical trial.

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Conditions

The condition(s) this trial relates to.

Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post operative cognitive dysfunction Post operative delerium

How to take part

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  1. The places running it

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  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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  3. A doctor treating you

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Contacts and locations

Locations

  • Hospital Clínico de la Universidad de Chile

    Santiago, Santiago Metropolitan, 8320000, Chile

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