Simple nasal sprays may shield Seniors' brains after bypass
NCT ID NCT06741566
First seen May 07, 2026
Summary
This study tests whether giving insulin or dexmedetomidine as a nasal spray before surgery can prevent early confusion and memory problems after coronary artery bypass grafting. The trial will enroll 150 adults aged 60 and older. Participants will receive one of the two nasal sprays or a placebo twice daily for two days before their operation.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fayoum university
RECRUITINGAl Fayyum, Egypt
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intranasal insulin or intranasal dexmedetomidine
What this could lead to
If it works, this could point toward a simple, low-cost way to prevent mental decline after heart bypass surgery.
What could go wrong
This is a very early (Phase 1) trial with only 150 people, so results may not be conclusive. The treatments might not work or could cause side effects like slow heart rate or cough.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.