Race to slow blinding eye disease in major drug trial

NCT ID NCT06541704

Recruiting now Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing two investigational drugs, pozelimab and cemdisiran, to see if they can slow down the progression of geographic atrophy, a late-stage form of age-related macular degeneration that causes permanent central vision loss. The trial will involve about 975 participants who will receive either the drug combination, one of the drugs alone, or a placebo via injection under the skin. The main goal is to measure whether the treatments reduce the rate at which the damaged area in the eye grows over time.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

Advanced Research
RECRUITING

Coral Springs, Florida, 33067, United States
American Institute of Research
RECRUITING

Los Angeles, California, 90017, United States
Associated Retina Consultants
RECRUITING

Phoenix, Arizona, 85020, United States
Augenzentrum Frankfurt
RECRUITING

Frankfurt am Main, Hesse, 60549, Germany
Austin Clinical Research LLC
RECRUITING

Austin, Texas, 78750, United States
Austin Research Center for Retina
RECRUITING

Austin, Texas, 78705, United States
Austin Retina Associates
RECRUITING

Austin, Texas, 78705, United States
Austin Retina Associates
RECRUITING

Round Rock, Texas, 78681, United States
Azienda Ospedaliero Universitaria Careggi
RECRUITING

Florence, Tuscany, 50134, Italy
Azienda Ospedaliero Universitaria delle Marche
RECRUITING

Ancona, 60126, Italy
Barnet Dulaney Perkins Eye Center
RECRUITING

Phoenix, Arizona, 85016, United States
Barnet Dulaney Perkins Eye Center-Ophthamalogy
RECRUITING

Chandler, Arizona, 85224, United States
Bascom Palmer Eye Institute
RECRUITING

Naples, Florida, 34103, United States
Bellvitge University Hospital
RECRUITING

L'Hospitalet de Llobregat, Barcelona, 8907, Spain
Black Hills Regional Eye Institute
RECRUITING

Rapid City, South Dakota, 57701, United States
Budapest Retina Associates
RECRUITING

Budapest, 1133, Hungary
California Eye Specialists Medical Group Inc.
RECRUITING

Pasadena, California, 91107, United States
California Eye Specialists Medical Group, Inc.
RECRUITING

Redlands, California, 92373, United States
California Retina Consultants
RECRUITING

Oxnard, California, 93036, United States
Caminomed
RECRUITING

Tarnowskie Góry, Silesian Voivodeship, 42-600, Poland
Cascade Medical Research Institute LLC
RECRUITING

Springfield, Oregon, 97477, United States
Center for Retina and Macular Disease
RECRUITING

Winter Haven, Florida, 33880, United States
Centre Hospitalier Intercommunal de Creteil
RECRUITING

Créteil, 94010, France
Centre Hospitalier Universitaire De Poitiers
RECRUITING

Poitiers, Nouvelle-Aquitaine, 86000, France
Centre Hospitalier Universitaire Francois Mitterrand
RECRUITING

Dijon, 21000, France
Centre Hospitalier Universitaire de Nantes
RECRUITING

Nantes, 44000, France
Centre Hospitalier Universitaire de Nice
RECRUITING

Nice, Alpes Maritimes, 6002, France
Centre Hospitalier Universitaire de Quebec Universite Laval
RECRUITING

Québec, G1S 4L8, Canada
Centre Monticelli Paradis
RECRUITING

Marseille, 13008, France
Centro de Oftalmologia Barraquer
RECRUITING

Barcelona, 08021, Spain
Centrum Diagnostyki I Mikrochirurgii Oka Lens Sp zoo
RECRUITING

Olsztyn, Warmian-Masurian Voivodeship, 10-424, Poland
Charite - Universitaetsmedizin Berlin
RECRUITING

Berlin, Brandenburg, 12203, Germany
Charleston Neuroscience Institute LLC
RECRUITING

Ladson, South Carolina, 29456, United States
Charleston Neuroscience Institute, LLC
RECRUITING

Mt. Pleasant, South Carolina, 29464, United States
Cincinnati Eye Institute
RECRUITING

Cincinnati, Ohio, 45242, United States
ClearVista Clinical Research, Retina Center Tampa Bay
RECRUITING

Hudson, Florida, 34667, United States
Colorado Retina - Lakewood
RECRUITING

Lakewood, Colorado, 80228, United States
Cumberland Valley Retina Consultants-Ophthalmology
RECRUITING

Hagerstown, Maryland, 21740, United States
Deep Blue Retina Clinical Research PLLC
RECRUITING

Southaven, Mississippi, 38671, United States
Desert Retina Consultants
RECRUITING

Palm Desert, California, 92211, United States
Dietrich Bonhoeffer Klinikum
RECRUITING

Neubrandenburg, Mecklenburg-Vorpommern, 17036, Germany
Erie Retinal Surgery & Erie Retina Research
RECRUITING

Erie, Pennsylvania, 16507, United States
Eye Assoc. of NE LA dba Haik Humble Eye Ctr
RECRUITING

West Monroe, Louisiana, 71291, United States
Eye Associates of Northeast Louisiana dba Haik Humble Eye Center
RECRUITING

West Monroe, Louisiana, 71291, United States
Eye Associates of Pinellas
RECRUITING

Pinellas Park, Florida, 33782, United States
Eye Medical Center of Fresno
RECRUITING

Fresno, California, 93720, United States
Eye care Center of Northern Colorado doing business as Advanced Vision Research Institute
RECRUITING

Longmont, Colorado, 80503, United States
EyeHealth Northwest
RECRUITING

Portland, Oregon, 97225, United States
Florida Retina Consultants
RECRUITING

Lakeland, Florida, 33805, United States
Florida Retina Institute - Orlando
RECRUITING

Orlando, Florida, 32806, United States
Florida Retina Institute, Jacksonville Perimeter Park- Ophthalmology
RECRUITING

Jacksonville, Florida, 32216, United States
Fondazione G.B.Bietti Per Lo Studio E La Ricerca In Oftalmologia
RECRUITING

Rome, 00184, Italy
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
RECRUITING

Milan, Lombardy, 20122, Italy
Fondazione Policlinico Gemelli
RECRUITING

Rome, Lazio, 00168, Italy
Fundacion Aiken De La Comunitat Valenciana
RECRUITING

Valencia, 46004, Spain
Ganglion Medical Center
RECRUITING

Pécs, Baranya, 7621, Hungary
Georgia Retina - Marietta
RECRUITING

Marietta, Georgia, 30060, United States
Graystone Eye
RECRUITING

Hickory, North Carolina, 28602, United States
Hopital De La Croix-Rousse
RECRUITING

Lyon, 69317, France
Hopital Lariboisiere
RECRUITING

Paris, 75010, France
Hopital Saint Joseph
RECRUITING

Marseille, Bouches Du Rhone, 13008, France
Hospital Arruzafa
RECRUITING

Córdoba, Andalusia, 14012, Spain
Hospital Clinico Universitario Lozano Blesa. IIS Aragon
RECRUITING

Zaragoza, 50009, Spain
Hospital Universitario Virgen Macarena
RECRUITING

Seville, 41009, Spain
Hospital de Terrassa (Consorci Sanitari de Terrassa)
RECRUITING

Terrassa, Barcelona, 08227, Spain
IRCCS MultiMedica
RECRUITING

Milan, Lombardy, 20123, Italy
Illinois Retina Associates
RECRUITING

Oak Park, Illinois, 60304, United States
Imperial College Healthcare NHS Trust
RECRUITING

London, NW1 5QH, United Kingdom
Institut Catala De Retina S.L.
RECRUITING

Barcelona, 8022, Spain
Instituto de Microcirugia Ocular
RECRUITING

Barcelona, 08035, Spain
Kaiser Permanente Los Angeles Medical Center
RECRUITING

Los Angeles, California, 90027, United States
Klinik fur Augenheilkunde Universitatsklinikum Dusseldorf
RECRUITING

Düsseldorf, North Rhine-Westphalia, 40225, Germany
Knappschaftsklinikum Saar GmbH- Eye Clnic Sulzbach
RECRUITING

Sulzbach, Saarland, 66280, Germany
Liverpool University Hospitals NHS Foundation Trust-Royal Liverpool University Hospital, St Paul's Eye Unit-Ophthalmology
RECRUITING

Liverpool, Merseyside, L7 8XP, United Kingdom
Macula Retina Vitreous Research Institute
RECRUITING

Torrance, California, 90503, United States
MaculaCare, PLLC
RECRUITING

New York, New York, 10021, United States
Massachusetts Eye And Ear Infirmary
RECRUITING

Boston, Massachusetts, 02114, United States
Medical Center Ophthalmology Associates
RECRUITING

San Antonio, Texas, 78240, United States
Medical University Graz
RECRUITING

Graz, Styria, 8036, Austria
Medical University of Vienna
RECRUITING

Vienna, 1090, Austria
Mid Atlantic Retina
RECRUITING

Bethlehem, Pennsylvania, 18017, United States
Mid Atlantic Retina - Cherry Hill
RECRUITING

Cherry Hill, New Jersey, 08034, United States
Mid Atlantic Retina Specialist
RECRUITING

Hagerstown, Maryland, 21740, United States
Mid Atlantic Retina, Wills Eye Hospital
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
Midwest Retina, Inc
RECRUITING

Dublin, Ohio, 43016, United States
Miguel Servet University Hospital
RECRUITING

Zaragoza, 50009, Spain
Mississippi Retina Associates
RECRUITING

Madison, Mississippi, 39110, United States
Moorfields Eye Hospital NHS Foundation Trust, Moorfields Eye Hospital
RECRUITING

London, EC1V 2PD, United Kingdom
NC Retina Associates
RECRUITING

Cary, North Carolina, 27511, United States
National Ophthalmic Research Institute
RECRUITING

Fort Myers, Florida, 33912, United States
New England Retina Consultants, PC
RECRUITING

Springfield, Massachusetts, 01107, United States
New Jersey Retina
RECRUITING

Teaneck, New Jersey, 07666, United States
New Jersey Retina
RECRUITING

Toms River, New Jersey, 08755, United States
New York Ear & Eye- East 85th
RECRUITING

New York, New York, 10028, United States
North Carolina Retina Associates
RECRUITING

Wake Forest, North Carolina, 27587, United States
Northern California Retina Vitreous Associates Medical Group, Inc.
RECRUITING

Mountain View, California, 94040, United States
OHSU-Casey Eye Institute, Marquam Hill-Ophthalmology
RECRUITING

Portland, Oregon, 97239, United States
Ochsner Health
RECRUITING

New Orleans, Louisiana, 70121, United States
Oftalmika Sp. z o.o.
RECRUITING

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-631, Poland
Oftalvist Clinic. IMED Hospital
RECRUITING

Burjassot, Valencia, 46100, Spain
Opthalmic Consultants of Boston
RECRUITING

Boston, Massachusetts, 02114, United States
Optic Eye Care
RECRUITING

Rowland Heights, California, 91748, United States
Orange County Retina Medical Group
RECRUITING

Santa Ana, California, 92705, United States
Ospedale San Raffaele (HSR) - Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS)
RECRUITING

Milan, Milano, 20132, Italy
Palmetto Retina Center
RECRUITING

West Columbia, South Carolina, 29169, United States
Piedmont Eye Center
RECRUITING

Lynchburg, Virginia, 24502, United States
Piedmont Retina Specialist
RECRUITING

Winston-Salem, North Carolina, 27103, United States
Red River Research Partners (Formerly AXIS Clinical)
RECRUITING

Plano, Texas, 75024, United States
Retina Associates New Orleans
RECRUITING

Metairie, Louisiana, 70006, United States
Retina Associates Of Utah Retina Specialist
RECRUITING

Salt Lake City, Utah, 84107, United States
Retina Associates of New York, Upper East Side
RECRUITING

New York, New York, 10075, United States
Retina Associates of South Texas
RECRUITING

San Antonio, Texas, 78240, United States
Retina Associates of Tuscan
RECRUITING

Tucson, Arizona, 85712, United States
Retina Associates, LLC
RECRUITING

Lenexa, Kansas, 66215, United States
Retina Care Specialists
RECRUITING

Palm Beach Gardens, Florida, 33410, United States
Retina Center of Texas
RECRUITING

Southlake, Texas, 76092, United States
Retina Centre of Ottawa - Department of Ophthalmology
RECRUITING

Ottawa, Ontario, K2B 7E9, Canada
Retina Consultants San Diego
RECRUITING

Poway, California, 92064, United States
Retina Consultants Texas
RECRUITING

Bellaire, Texas, 77401, United States
Retina Consultants Texas
RECRUITING

The Woodlands, Texas, 77384, United States
Retina Consultants of Carolina
RECRUITING

Greenville, South Carolina, 29605, United States
Retina Consultants of Orange County
RECRUITING

Fullerton, California, 92835, United States
Retina Consultants of Southern Colorado
RECRUITING

Colorado Springs, Colorado, 80909, United States
Retina Consultants of Texas
RECRUITING

Katy, Texas, 77494, United States
Retina Consultants of Texas
RECRUITING

San Antonio, Texas, 78240, United States
Retina Consultants of Texas Brown Retina Institute
RECRUITING

San Antonio, Texas, 78251, United States
Retina Foundation of the Southwest
RECRUITING

Dallas, Texas, 75231, United States
Retina Group of Florida
RECRUITING

Fort Lauderdale, Florida, 33308, United States
Retina Group of Florida, RAS-Sarasota Retina Center-Ophthalmology
RECRUITING

Sarasota, Florida, 34232, United States
Retina Group of New England
TERMINATED

Waterford, Connecticut, 06385, United States
Retina Group of Washington
RECRUITING

Fairfax, Virginia, 22031, United States
Retina Institute of Virginia
COMPLETED

Richmond, Virginia, 23235, United States
Retina Macula Institute of Arizona
RECRUITING

Scottsdale, Arizona, 85255, United States
Retina Northwest, The Highlands Building
RECRUITING

Portland, Oregon, 97221, United States
Retina Partners of Northwest Arkansas, PLLC
RECRUITING

Springdale, Arkansas, 72764, United States
Retina Research Institute of Texas
RECRUITING

Abilene, Texas, 79606, United States
Retina Research Institute, LLC
RECRUITING

St Louis, Missouri, 63144, United States
Retina Specialists of Beverly Hills- Department of Ophthalmology
RECRUITING

Beverly Hills, California, 90212, United States
Retina Specialists of Colorado - Denver
RECRUITING

Denver, Colorado, 80222, United States
Retina Vitreous Associates Medical Group
RECRUITING

Beverly Hills, California, 90211, United States
Retina Vitreous Associates of Florida Saint Petersburg
RECRUITING

St. Petersburg, Florida, 33711, United States
Retina Vitreous Center - Edmond
RECRUITING

Edmond, Oklahoma, 73013, United States
Retina Vitreous Surgeons of Central New York, PC
RECRUITING

Liverpool, New York, 13088, United States
Retinal Consultants Medical Group (RCMG) - Greenback Lane Retina Center
RECRUITING

Sacramento, California, 95841, United States
Retinal Consultants Medical Group Inc Modesto
RECRUITING

Modesto, California, 95356, United States
Retinal Research Institute
RECRUITING

Phoenix, Arizona, 85053, United States
Retinal Vitreal Consultants
RECRUITING

Chicago, Illinois, 60616, United States
Rocky Mountain Retina Consultants
RECRUITING

Salt Lake City, Utah, 84107, United States
Ross Davis Retina
RECRUITING

Metairie, Louisiana, 70006, United States
Saarland University Medical Center
RECRUITING

Homburg, Saarland, 66421, Germany
Salehi Retina Institute dba Retina Associates of Southern California
RECRUITING

Huntington Beach, California, 92647, United States
Salt Lake Retina- Ophthalmology
RECRUITING

West Jordan, Utah, 84088, United States
Seeta Eye center
RECRUITING

Poughkeepsie, New York, 12603, United States
Semmelweis University
RECRUITING

Budapest, 1085, Hungary
Sewickley Eye Group
RECRUITING

Sewickley, Pennsylvania, 15143, United States
Sight MD
RECRUITING

Brentwood, New York, 11717, United States
South Coast Retina Center
RECRUITING

Long Beach, California, 90807, United States
Southeast Retina Center
RECRUITING

Augusta, Georgia, 30909, United States
Southeastern Retina Associates
RECRUITING

Bristol, Virginia, 24201, United States
Southwest Retina Research Center
RECRUITING

Durango, Colorado, 81303, United States
Spokane Eye Clinical Research
RECRUITING

Spokane, Washington, 99204, United States
Springfield Clinic Main Campus East
RECRUITING

Springfield, Illinois, 62703, United States
St. Franziskus-Hospital
RECRUITING

Münster, 48145, Germany
Star Retina PLLC
RECRUITING

Burleson, Texas, 76028, United States
Tennessee Retina, PC
RECRUITING

Nashville, Tennessee, 37203, United States
Texas Retina Associates
RECRUITING

Dallas, Texas, 75231, United States
The Newcastle Upon Tyne Hospitals NHS Foundation Trust
RECRUITING

Newcastle upon Tyne, NE1 4LP, United Kingdom
The Ohio State University
RECRUITING

Columbus, Ohio, 43212, United States
The Retina Care Center
RECRUITING

Baltimore, Maryland, 21209, United States
The Retina Group of Washington
RECRUITING

Chevy Chase, Maryland, 20815, United States
The Retina Partners
RECRUITING

Encino, California, 91436, United States
The University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States
Toulouse University Hospital
RECRUITING

Toulouse, Occitanie, 31059, France
Tulsa Retina Consultants
RECRUITING

Tulsa, Oklahoma, 74114, United States
Tyler Retina Research Institute- Ophthalmology
RECRUITING

Tyler, Texas, 75703, United States
UC Davis Health Eye Center
RECRUITING

Sacramento, California, 95817, United States
Universita degli Studi di Milano
RECRUITING

Milan, 20157, Italy
Universitaetsklinikum Marburg, Klinik fuer Augenheilkunde
RECRUITING

Marburg, Hesse, 35043, Germany
Universitaetsklinikum Muenster
RECRUITING

Münster, North Rhine-Westphalia, 48149, Germany
Universitatsklinikum Bonn
RECRUITING

Bonn, North Rhine-Westphalia, 53127, Germany
University Hospital Hamburg Eppendorf
RECRUITING

Hamburg, 20246, Germany
University Hospital PTV
RECRUITING

Rome, Lazio, 00133, Italy
University Hospitals Bristol NHS Foundation Trust
RECRUITING

Bristol, BS1 2LX, United Kingdom
University Hospitals Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University Medical Center of the Johannes Gutenberg-University Mainz
RECRUITING

Mainz, 55131, Germany
University Of Debrecen, Hungary
RECRUITING

Debrecen, Hajdú-Bihar, 4032, Hungary
University Of Szeged
RECRUITING

Szeged, Csongrad-Csanad, 6720, Hungary
University Retina and Macula Associates PC - Lemont
RECRUITING

Lemont, Illinois, 60439, United States
University of California Irvine
RECRUITING

Irvine, California, 92617, United States
University of California San Diego, Jacobs Retina Center
RECRUITING

La Jolla, California, 92093, United States
University of Colorado
RECRUITING

Aurora, Colorado, 80045, United States
University of Illinois at Chicago
RECRUITING

Chicago, Illinois, 60612, United States
University of Louisville
RECRUITING

Louisville, Kentucky, 40202, United States
University of New Mexico, HSC
RECRUITING

Albuquerque, New Mexico, 87131, United States
University of South Florida Ophthalmology
RECRUITING

Tampa, Florida, 33612, United States
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
University of Ulm
RECRUITING

Ulm, Baden-Wurttemberg, 89081, Germany
University of Vermont
RECRUITING

Burlington, Vermont, 05401, United States
VIROS - Vienna Institute for Research in Ocular Surgery
RECRUITING

Vienna, 1140, Austria
Valley Retina Institute, P.A.
RECRUITING

McAllen, Texas, 78503, United States
Vanderbilt Eye Institute
RECRUITING

Nashville, Tennessee, 37232, United States
Verum Research LLC
RECRUITING

Eugene, Oregon, 97401, United States
Virginia Eye Institute
RECRUITING

Richmond, Virginia, 23226, United States
Vision Research Center at Eye Associates of New Mexico
RECRUITING

Albuquerque, New Mexico, 87109, United States
Vision Research Solutions - the Eye Institute
RECRUITING

Philadelphia, Pennsylvania, 19141, United States
Vrmg Inc
RECRUITING

Sacramento, California, 95825, United States
West Coast Retina Medical Group, Inc.
RECRUITING

San Francisco, California, 94109, United States
West Virginia University Eye Institute
RECRUITING

Morgantown, West Virginia, 26506, United States
Western Carolina Retinal Associates
RECRUITING

Asheville, North Carolina, 28803, United States
York and Scarborough Teaching Hospitals NHS Foundation Trust
RECRUITING

York, North Yorkshire, YP31 8HE, United Kingdom

Conditions

Explore the condition pages connected to this study.