Pee and blood may replace painful muscle biopsies for muscular dystrophy

NCT ID NCT05020002

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find less invasive ways to measure disease activity in myotonic dystrophy by looking for RNA markers in blood and urine instead of taking muscle biopsies. Researchers will compare samples from 215 people with and without the condition to see if these markers can reliably track disease severity. The goal is to develop a simple test that could make monitoring the disease easier and more comfortable for patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02129, United States

  • University of Texas Southwestern

    RECRUITING

    Dallas, Texas, 75390, United States

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