Pee and blood may replace painful muscle biopsies for duchenne kids

NCT ID NCT05016908

Recruiting now Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find less invasive ways to measure Duchenne muscular dystrophy activity. Researchers will collect urine and blood samples from 100 participants, including boys with Duchenne or Becker muscular dystrophy and healthy adults. They will look for RNA biomarkers that could indicate disease severity without needing a muscle biopsy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple blood or urine test to monitor Duchenne muscular dystrophy without needing painful muscle biopsies.
What could go wrong: This is an early observational study, not a treatment trial. It may not find reliable biomarkers, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BECKER MUSCULAR DYSTROPHY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Becker muscular dystrophy Duchenne muscular dystrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DUCHENNE MUSCULAR DYSTROPHY

Contacts and locations

Locations

Boston Children's Hospital
ACTIVE_NOT_RECRUITING

Boston, Massachusetts, 02115, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02129, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.