Pee and blood may replace painful muscle biopsies for duchenne kids
NCT ID NCT05016908
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to find less invasive ways to measure Duchenne muscular dystrophy activity. Researchers will collect urine and blood samples from 100 participants, including boys with Duchenne or Becker muscular dystrophy and healthy adults. They will look for RNA biomarkers that could indicate disease severity without needing a muscle biopsy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a simple blood or urine test to monitor Duchenne muscular dystrophy without needing painful muscle biopsies.
What could go wrong
This is an early observational study, not a treatment trial. It may not find reliable biomarkers, and results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Boston Children's Hospital
ACTIVE_NOT_RECRUITINGBoston, Massachusetts, 02115, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02129, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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