Can a longer course of TARPEYO tame kidney disease?

NCT ID NCT06712407

Recruiting now Disease control Sponsor: Calliditas Therapeutics AB Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether taking TARPEYO (budesonide) for a longer period helps adults with IgA nephropathy, a kidney disease. Participants have already taken the drug for 9 months and will now take it for another 15 months. The main goal is to see if protein levels in urine stay lower, which would suggest less kidney damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: budesonide (delayed-release capsules)
What this could lead to: If successful, this could show that taking TARPEYO for a longer period helps control kidney damage in IgA nephropathy, potentially reducing the need for more aggressive treatments.
What could go wrong: This is a small, early-phase 4 study with only 60 participants, so results may not apply to everyone. The drug may not provide additional benefit beyond the initial 9 months, and side effects from long-term steroid use are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease IgA glomerulonephritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IGA NEPHROPATHY

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Advanced Renal Care Institute
RECRUITING

Mayagüez, 00680, Puerto Rico
Arizona Kidney Disease & Hypertension Centers (AKDHC)
RECRUITING

Glendale, Arizona, 85306, United States
Boston Medical Center; Boston University Chobanian & Avedisian School of Medicine
RECRUITING

Boston, Massachusetts, 02118, United States
Central Florida Kidney Specialists
RECRUITING

Orlando, Florida, 32819, United States
Chinatown Kidney Care, PLLC
RECRUITING

New York, New York, 10013, United States
Cobb Nephrology Hypertension Associates, PC
RECRUITING

Austell, Georgia, 30106, United States
Dallas Nephrology Associates McKinney
RECRUITING

McKinney, Texas, 75069, United States
Dallas Renal Group
RECRUITING

Dallas, Texas, 75230, United States
Florida Kidney Physicians
RECRUITING

Boca Raton, Florida, 33431, United States
Georgia Nephrology
RECRUITING

Lawrenceville, Georgia, 30046, United States
Icahn School of Medicine at Mount Sinai
RECRUITING

New York, New York, 10029, United States
Loma Linda University
RECRUITING

San Bernardino, California, 92408, United States
MedResearch Inc
RECRUITING

El Paso, Texas, 79902, United States
Memorial Hermann Houston
RECRUITING

Houston, Texas, 77054, United States
New York Nephrology Vasculitis and Glomerular Center
RECRUITING

Clifton Park, New York, 12065, United States
North Carolina Nephrology, P.A
RECRUITING

Raleigh, North Carolina, 27609, United States
Ochsner Health, New Orleans
RECRUITING

New Orleans, Louisiana, 70121, United States
Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States
Oregon Health & Science University (OHSU) - Nephrology and Hypertension Clinic
RECRUITING

Portland, Oregon, 97239, United States
Permian Basin Kidney Center
RECRUITING

Odessa, Texas, 79761, United States
Prolato Clinical Research Center
RECRUITING

Houston, Texas, 77054, United States
Renal Medical Associates
RECRUITING

Albuquerque, New Mexico, 87109, United States
Southeastern Clinical Research Institute, LLC
RECRUITING

Augusta, Georgia, 30904, United States
Stanford University
RECRUITING

Stanford, California, 94305, United States
The Kidney Institute/Houston
RECRUITING

Houston, Texas, 77090, United States
The Medical Research Group, Inc.
RECRUITING

Fresno, California, 93720, United States
The University of Texas Medical Branch UTMB
RECRUITING

Galveston, Texas, 77555, United States
UCI Health-UCI Medical Center
RECRUITING

Orange, California, 92868, United States
UCSF Health-UCSF Medical Center-Parnassus - Nephrology and Hypertension Faculty Practice
RECRUITING

San Francisco, California, 94143, United States
Univ of Alabama/Birmingham
RECRUITING

Birmingham, Alabama, 35297, United States
University of Colorado Hospital (UCH) - Kidney Disease and Hypertension Clinic - Anschutz Medical Campus Location
RECRUITING

Aurora, Colorado, 80045, United States
University of Louisville
RECRUITING

Louisville, Kentucky, 40208, United States
University of Maryland Division of Nephrology
RECRUITING

Baltimore, Maryland, 21201, United States
University of Minnesota Health Fairview
RECRUITING

Minneapolis, Minnesota, 55455, United States
University of New Mexico
RECRUITING

Albuquerque, New Mexico, 87106, United States
University of Pennsylvania Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Washington University in St. Louis
RECRUITING

St Louis, Missouri, 63130, United States
Yale University Nephrology Clinical Trials Program
RECRUITING

New Haven, Connecticut, 06510, United States

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