Could a Once-a-Year cholera shot be just as good?

NCT ID NCT07487077

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study in Nairobi, Kenya, is testing whether giving the oral cholera vaccine Euvichol-S at longer intervals (3 months or 12 months) works as well as the standard 2-week schedule. Over 1,000 healthy participants aged 1 year and older will be randomly assigned to one of three dosing schedules. The goal is to see if flexible timing can still protect against cholera, which could make vaccination campaigns easier in areas where outbreaks are common.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Euvichol-S oral cholera vaccine

What this could lead to

If successful, this could allow more flexible vaccination schedules, making it easier to protect communities against cholera in outbreak-prone areas.

What could go wrong

This is a Phase 4 trial, but it is still early for these specific dosing schedules. The results may not apply to other regions or populations, and the vaccine may not provide the same level of protection with longer intervals.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cholera prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • KEMRI

    RECRUITING

    Nairobi, Kenya

    Contact