New cholera vaccine trial aims to protect families in High-Risk areas

NCT ID NCT07509047

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new cholera vaccine (OSP:rTTHc CCV) in 390 healthy adults and children aged 1 to 45 in a region where cholera is common. The goal is to see if the vaccine is safe and triggers a strong immune response. Some participants get the vaccine with or without an adjuvant (alum), while others get a standard cholera vaccine or a placebo. Results will help decide the best dose and schedule for future use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
OSP:rTTHc cholera conjugate vaccine (CCV) with or without aluminum phosphate adjuvant
What this could lead to
If successful, this could lead to a more effective cholera vaccine that protects adults and children with fewer doses.
What could go wrong
This is a phase II trial with 390 participants, so results are still early. The vaccine may not produce strong enough immunity or could have side effects not seen yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • KAVI-Institute of Clinical Research, University

    RECRUITING

    Nairobi, Kenyatta National Hospital Complex, 19676, Kenya

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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