Could extra antibiotics help prolong pregnancy after early water break?
NCT ID NCT07669207
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether adding extra doses of the antibiotic azithromycin to standard care can improve outcomes for pregnant people whose water breaks very early (between 22 and 28 weeks). Thirty participants will be randomly assigned to receive either the standard antibiotic regimen or the standard plus seven additional azithromycin doses. The main goal is to see if such a study is feasible, not yet to prove the treatment works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Azithromycin (antibiotic)
What this could lead to
If it works, this could point toward a better antibiotic regimen to prolong pregnancy and improve outcomes after preterm membrane rupture.
What could go wrong
This is a very small pilot study (30 people) focused on feasibility, not effectiveness. It may not show clear benefits, and extra antibiotics could increase side effects or bacterial resistance.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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University of Pittsburgh Magee-Womens Hospital
Pittsburgh, Pennsylvania, 15217, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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