New hope for dravet syndrome: expanded access to seizure drug stiripentol

NCT ID NCT01983722

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This program provides expanded access to the drug stiripentol for people aged 6 months and older with Dravet syndrome, a severe form of epilepsy. The goal is to help control seizures that do not respond to other treatments. Participants must have a confirmed diagnosis and meet safety criteria, such as no severe liver or kidney problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Stiripentol
What this could lead to
If successful, this program could offer a treatment option to reduce seizures in patients with Dravet syndrome who have not responded to other therapies.
What could go wrong
This is an expanded access program, not a formal trial, so evidence on effectiveness and safety is limited. Stiripentol may cause side effects like drowsiness or allergic reactions.

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Conditions

The condition(s) this trial relates to.

Dravet syndrome Epilepsies, Myoclonic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

More trials for these conditions

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