Last-Resort cell therapy offered to sarcoma patients

NCT ID NCT06617572

AVAILABLE Disease control Sponsor: USWM CT, LLC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times

Summary

This expanded access program offers a cell therapy called afamitresgene autoleucel (afami-cel) to people with synovial sarcoma or myxoid liposarcoma whose manufactured dose didn't meet commercial standards. Eligible patients have no other feasible treatment options. The therapy is given as a single intravenous infusion.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: afamitresgene autoleucel (afami-cel), a cell therapy made from the patient's own immune cells
What this could lead to: If this works, it could provide a treatment option for patients with synovial sarcoma or myxoid liposarcoma who have no other alternatives.
What could go wrong: This is an expanded access program, not a formal trial, so data on effectiveness and safety is limited. The product does not meet commercial specifications, meaning its quality or potency may be lower than standard.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

myxoid liposarcoma synovial sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYXOID LIPOSARCOMA SYNOVIAL SARCOMA

Contacts and locations

Locations

Dana-Farber Cancer Institute
AVAILABLE

Boston, Massachusetts, 02215, United States
Fox Chase Cancer Center
AVAILABLE

Philadelphia, Pennsylvania, 19111, United States
MD Anderson Cancer Center
AVAILABLE

Houston, Texas, 77030, United States
Massachusetts General Hospital
AVAILABLE

Boston, Massachusetts, 02144, United States
Mayo Arizona
AVAILABLE

Phoenix, Arizona, 85259, United States
Mayo Florida
AVAILABLE

Jacksonville, Florida, 32224, United States
Mayo Rochester
AVAILABLE

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Cancer Centre
AVAILABLE

New York, New York, 10065, United States
Moffit Cancer Center
AVAILABLE

Tampa, Florida, 33612, United States
Northwestern University Feinberg School of Medicine
AVAILABLE

Chicago, Illinois, 60601, United States
Stanford Hospital and Clinics
AVAILABLE

Stanford, California, 94305, United States

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