Can exosomes reverse facial aging? new study tests microneedling combo

NCT ID NCT07372001

Completed Symptom relief Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 4 trial tested whether applying exosomes (tiny particles from cells) to the face with a microneedling device can reduce signs of skin aging. Thirty men and women over 50 with wrinkles and other aging signs received three treatments, each four weeks apart. Researchers measured changes in skin elasticity, wrinkles, roughness, pigmentation, redness, and pore size, along with patient satisfaction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Topical lyophilized exosomes applied with a microneedling device
What this could lead to: If it works, this could offer a new cosmetic option to reduce signs of facial skin aging like wrinkles and roughness.
What could go wrong: This is a small, completed Phase 4 study with only 30 participants and no control group, so results may not be generalizable. Risks include allergic reactions or irritation from the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SKIN AGING

Contacts and locations

Locations

Instituto de Oftalmología F.A.P. Conde de Valenciana, I.A.P.

Mexico City, Mexico City, 08800, Mexico

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