Can genetic screening help prevent cancer in underserved communities?
NCT ID NCT03426878
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looked at whether offering exome sequencing (a detailed genetic test) along with tailored genetic counseling helps people at high risk for hereditary cancer syndromes understand their risk and take action. Nearly 1,000 adults from diverse backgrounds in Colorado and Oregon participated. The goal was to see how well this approach works in real-world primary care settings.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
exome sequencing and genetic counseling
What this could lead to
If successful, this could help tailor cancer risk assessment and genetic counseling for diverse populations, potentially leading to earlier detection and prevention.
What could go wrong
This is a completed observational study with a small sample size (967 participants) and focuses on feasibility and utility, not treatment outcomes. Results may not apply to all populations.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Denver Health
Denver, Colorado, 80204, United States
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Kaiser Permanente Center for Health Research
Portland, Oregon, 97227, United States