New drug aims to prevent Crohn's relapse after surgery
NCT ID NCT06925061
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests an oral drug called EXL01 to see if it can prevent Crohn's disease from coming back after bowel surgery. About 80 adults who recently had surgery for Crohn's will receive either EXL01 or a placebo for up to 24 weeks. Doctors will use a camera to check the bowel for signs of disease at 6 months after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
EXL01 (an oral drug)
What this could lead to
If it works, this could point toward a new way to prevent Crohn's disease from coming back after surgery.
What could go wrong
This is an early Phase 2 trial with only 80 people, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU Clermont-Ferrand
RECRUITINGClermont-Ferrand, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Lille
RECRUITINGLille, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Marseille Nord
RECRUITINGMarseille, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Montpellier
RECRUITINGMontpellier, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Nancy
RECRUITINGNancy, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Nantes
RECRUITINGNantes, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Nice Archet 2
RECRUITINGNice, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Saint Louis
RECRUITINGParis, 75010, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospices civils Lyon Sud
RECRUITINGLyon, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Bicêtre
RECRUITINGLe Kremlin-Bicêtre, 94270, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Henri Mondor
RECRUITINGCréteil, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Saint Antoine
RECRUITINGParis, 75012, France
Contact Phone: •••-•••-•••• Email: •••••@•••••