Virtual reality cycling may sharpen brain function after TBI

NCT ID NCT04901286

Completed Knowledge-focused Sponsor: Kessler Foundation Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether a single session of moderate cycling, done in a lab, with a non-immersive virtual reality screen, or with a full immersive virtual reality headset, could improve thinking speed and multitasking in 24 adults with traumatic brain injury. Participants completed three different cycling sessions, and their cognitive performance was measured before and after. The goal was to see if the environment during exercise makes a difference for brain function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: moderate intensity aerobic exercise (cycling) with or without virtual reality environments
What this could lead to: If it works, this could point toward simple ways to boost cognitive function after brain injury using exercise and virtual reality.
What could go wrong: This is a small, early study with only 24 participants. The effects of exercise on cognition are often small, and the added benefit of virtual reality may not be significant.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TRAUMATIC BRAIN INJURY

Contacts and locations

Locations

Kessler Foundation

East Hanover, New Jersey, 07936, United States

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