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Exercise may ease nerve pain and keep legs strong in ovarian cancer patients on chemo

NCT ID NCT04997096

Recruiting now Symptom relief Sponsor: Dana-Farber Cancer Institute Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a 16-week, virtually supervised exercise program can help patients with ovarian or endometrial cancer maintain leg function and reduce chemotherapy-induced nerve damage. Thirty patients who have had surgery and are starting first-line chemo will be assigned to either the exercise group or a stretching control group. The main goal is to see if the program is feasible and if it improves mobility and reduces numbness or tingling in the hands and feet.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
aerobic and resistance exercise program
What this could lead to
If it works, this could point toward a simple, drug-free way to help cancer patients stay mobile and reduce nerve-related side effects during chemotherapy.
What could go wrong
This is a very small, early feasibility study with only 30 participants, so results may not apply to everyone. The exercise program may be too demanding for some patients.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrial carcinoma endometrium neoplasm ovarian cancer ovarian carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CANCER ENDOMETRIAL CANCER STAGE OVARIAN CANCER OVARIAN CANCER STAGE 3 OVARIAN CANCER STAGE III OVARIAN CANCER STAGE IV OVARIAN CARCINOMA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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