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Exercise and diet may ease nerve damage and fatigue during chemo

NCT ID NCT03885817

Symptom relief Sponsor: St. Olavs Hospital Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study tests whether a tailored exercise program and nutritional guidance can reduce peripheral neuropathy (nerve damage) and fatigue in people with colorectal cancer receiving chemotherapy. Participants follow a supervised exercise routine and monthly nutrition check-ins during their treatment. The goal is to improve quality of life by managing common side effects of chemotherapy.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
an exercise program and nutritional guidance
What this could lead to
If it works, this could offer a simple, drug-free way to ease nerve pain and tiredness during chemotherapy.
What could go wrong
This is a small, early-stage trial, so results may not apply to everyone. The benefits may be modest or hard to separate from standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

66 people

The number who actually took part.

Started

Mar 2019

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Radical resection for colon- or rectal cancer past 3 months, and scheduled for adjuvant, Oxaliplatin-based, combination chemotherapy. * Histologically confirmed adenocarcinoma. * Able to read and understand Norwegian. * Able to carry out the intervention. * Performance Status (PS) 0 - 2. Exclusion Criteria: * Serious comorbidities that contraindicate physical exercise, based on the treating physician's assessment. * Unable to give informed consent. * Treated for other cancer last 5 years prior to inclusion (with the exceptions of basal cell carcinoma of the skin and carcinoma in situ in the cervix). * Prior treatment with Oxaliplatin

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm Fatigue peripheral nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neoplasms, colorectal

Contacts and locations

Locations

  • Kreftklinikken, St Olavs Hospital

    Trondheim, Norway

  • Levanger sykehus

    Levanger, Norway

  • Sørlandet sykehus, Kristiansand

    Kristiansand, Norway

  • Ullevål

    Oslo, Norway

  • Ålesund sjukehus

    Ålesund, Norway

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