Exercise showdown: which workout best eases back pain in overweight men?
NCT ID NCT07688564
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This study compares three types of exercise—motor control, aerobic walking, and muscle strengthening—against education alone in overweight men with chronic low back pain. Over 12 weeks, researchers will measure how well the body's natural pain-fighting system works, along with pain levels, disability, and quality of life. The goal is to find which exercise approach offers the most relief for this specific group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- exercise programs (motor control, aerobic walking, muscle strengthening)
- What this could lead to
- If effective, these exercise programs could offer a drug-free way to reduce pain and improve daily function in overweight men with chronic low back pain.
- What could go wrong
- This is a relatively small trial focused on a specific group (overweight men), so results may not apply to others. Exercise benefits can vary widely, and the study may not find a clear winner among the approaches.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 156 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 59 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged ≥ 18 to \< 60 years. * Diagnosed with nonspecific CLBP that has persisted for over three months. * Overweight males (not obese), with a BMI between 25.0 and 29.9 kg/m² (the standard WHO/CDC classification). Excludes normal weight (\<25 kg/m²) and obesity (≥30 kg/m²) to focus on the mechanical and metabolic consequences of excess weight and to avoid confounding by significant comorbidities, mobility restrictions, or modified exercise tolerance that may skew CPM results. * Pain level greater than 4 on the Numerical Pain Rating Scale (NPRS). * Signs and symptoms indicating that a CS measurement is required must be present, with a CSI score of 40 or higher. * Psychological status will be screened with the Depression Anxiety Stress Scales-21 (DASS-21) to confirm the absence of clinically significant symptoms of depression, anxiety, or stress. Eligible participants will be overweight males aged 18 to 60 years with nonspecific CLBP who score within the normal range on all DASS-21 subscales. Participants with severe psychological distress will be excluded, while mild to moderate symptoms will be statistically controlled. Exclusion Criteria: * CLBP due to a recognized specific pathology (e.g., infection, tumor, osteoporosis, fracture, structural deformity, or inflammatory disorders such as ankylosing spondylitis, radiculopathy, or cauda equina syndrome). * Contraindications for physical activity participation. * A history of spine surgery or spine diseases that cause symptoms. * The presence of acute pain within 48 hours prior to the study date. * A history of using corticosteroids or other pain-affecting medications within the past two weeks is also required. * Participants must not have other long-term pain conditions, high blood pressure, Raynaud's disease, frostbite, open wounds, broken bones, serious illnesses such as cancer, or mental health problems. * Visual and/or hearing impairments. These criteria apply uniformly to all four study arms: MCE, AW, MSE, and the patient education (control) arm. These specific criteria ensure that the study group is homogeneous, which is important for examining how exercise interventions affect overweight males with nonspecific CLBP who exhibit central sensitization.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Physiotherapy Clinic at the College of Applied Medical Sciences, Najran University, Najran City, Saudi Arabia.
Najran, Najran Region, 61441, Saudi Arabia
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