Personalized exercise program shows promise for reducing fatigue in children with cancer

NCT ID NCT05289739

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a personalized exercise program could help children and teens undergoing cancer treatment feel less tired and improve their quality of life. Nearly 500 participants did age-appropriate exercises like strength, balance, and endurance training for 30–60 minutes, 3–5 times a week for about 8–10 weeks. The main goal was to see if fatigue scores improved during and after the program, with follow-up lasting one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
personalized exercise training (endurance, strength, flexibility, balance, coordination, and gait training)
What this could lead to
If it works, this could provide a safe, drug-free way to help children feel less tired and have a better quality of life during cancer treatment.
What could go wrong
This is a completed study, but exercise may be hard for very sick children, and benefits might vary widely. The results may not apply to all types of childhood cancer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Johannes-Gutenberg-University Medical Center

    Mainz, Rhineland-Palatinate, 55131, Germany

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