Pump iron, lift mood: new study tests weight training as depression treatment

NCT ID NCT06110897

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This study tests whether resistance exercise (like weight lifting) can reduce symptoms of major depression. Two hundred adults with depression will do either a high or low dose exercise program for 16 weeks. Researchers will measure changes in mood and brain blood flow to see if exercise works and how.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Iowa State University

    COMPLETED

    Ames, Iowa, 50010, United States

  • University of Wisconsin - Madison

    RECRUITING

    Madison, Wisconsin, 53705, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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