Exercise as medicine: new trial tests if workouts can lift depression
NCT ID NCT06450704
First seen Jan 09, 2026 · Last updated May 14, 2026 · Updated 24 times
Summary
This study looks at whether adding a structured exercise program to standard antidepressant treatment can improve symptoms of major depression. Researchers will also use brain scans and blood tests to understand how exercise might reduce inflammation and change brain activity. About 124 adults with moderate to severe depression will take part, with one group doing exercise and the other continuing their usual care.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital Universitario La Paz
RECRUITINGMadrid, Madrid, 28046, Spain
Contact Email: •••••@•••••
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Hospital Universitario Príncipe de Asturias
RECRUITINGAlcalá de Henares, Madrid, 28805, Spain
Contact Email: •••••@•••••
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Hospital Universitario Puerta de Hierro-Majadahonda
RECRUITINGMajadahonda, Madrid, 28222, Spain
Contact Email: •••••@•••••
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Hospital Universitario Ramón y Cajal
RECRUITINGMadrid, Madrid, 28034, Spain
Contact Email: •••••@•••••
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Hospital Universitario de La Princesa
RECRUITINGMadrid, Madrid, 28006, Spain
Contact Email: •••••@•••••
Conditions
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