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Exercise as brain medicine: could a workout sharpen the minds of those with bipolar disorder?

NCT ID NCT06560749

Recruiting now Disease control Sponsor: Beny Lafer Source: ClinicalTrials.gov ↗

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This trial tests whether a structured physical exercise program can improve memory, attention, and other thinking skills in adults with bipolar disorder who already have some cognitive difficulties. Participants will be randomly assigned to exercise or usual care, and researchers will measure changes in cognition, mood, quality of life, and physical fitness. The goal is to see if exercise can serve as a safe, accessible add-on treatment for the cognitive problems that often accompany bipolar disorder.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a structured physical exercise program
What this could lead to
If it works, this could point toward a drug-free way to help people with bipolar disorder think more clearly and feel better day-to-day.
What could go wrong
This is a small, early-stage study, so results may not apply to everyone. Exercise may not improve cognition more than other activities, and some people may find it hard to stick with the program.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bipolar disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIPOLAR DISORDER

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gabriel Okawa Belizario

    RECRUITING

    São Paulo, São Paulo, 05403-903, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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